FDA Breakthrough Device enabling remote monitoring and early intervention for patients with decompensated cirrhosis. Reduce hospital readmissions by up to 38% with continuous specialist care at home.
CirrhoCare® is the first multi-modal monitoring system designed to assess key complications of cirrhosis decompensation events with proprietary algorithms that present actionable insights for clinical decision making.
Intuitive smartphone app that seamlessly integrates with monitoring devices to track vital metrics including heart rate, blood pressure, weight, body water composition, and cognitive function through the CyberLiver Animal Recognition Test (CL-ART). Enables therapeutic interventions both pharmacological and non-pharmacological.
Proprietary algorithms analyse multi-modal data to detect early signs of decompensation events such as ascites, hepatic encephalopathy, infection and hypovolemia before they become critical, enabling timely therapeutic interventions including both pharmacological and non-pharmacological.
Comprehensive clinician dashboard provides real-time patient status overview, automated alerts, and decision support tools enabling specialists to make rapid, informed therapeutic interventions from anywhere.
Enables specialist hepatology care outside hospital settings, allowing for continuous monitoring regardless of location or proximity to specialised liver care centers. Like doing a ward round with patients in their homes.
Secure, bidirectional communication system between patients and healthcare providers ensures compliance, engagement, and improved support when needed.
Daily recording of multiple parameters: vital signs, sleep status, physical activity, cognitive function, self-reported wellbeing, and intake of food, fluid, and alcohol for holistic patient assessment.
A comprehensive approach to transforming cirrhosis care through continuous monitoring and early intervention, enabling proactive management of decompensated cirrhosis patients.
Before hospital discharge, patients receive a fully configured HealthKit including smartphone with SIM card, smartwatch, digital blood pressure monitor, bio-impedance weighing scales, a digital thermometer and access to digital diagnostic and assessment tools.
Patients use the HealthKit for recording the digital bio-markers and PROMs: vital signs, body composition, sleep patterns, physical activity, cognitive assessments, and patient-reported outcomes including fluid intake and wellbeing.
Advanced ML algorithms analyse collected data to identify patterns indicative of early decompensation. Automated alerts notify clinical teams for timely community-based interventions, preventing hospitalisations through proactive care management.
CirrhoCare® leverages commercially available wearable and sensors integrated with proprietary algorithms to deliver comprehensive remote patient monitoring and management for cirrhosis patients.
All wearables and sensors sync automatically with the CirrhoCare® platform for real-time data analysis, trend tracking, and clinical decision support through advanced machine learning algorithms.
Published research in the Journal of Hepatology demonstrates significant improvements in patient outcomes and healthcare resource utilization through CirrhoCare® management of decompensated cirrhosis patients.
Study Design: Prospective pilot study comparing 20 CirrhoCare® managed patients with 20 contemporaneous matched controls receiving standard care over 10.1 ± 2.4 weeks follow-up period.
Patient Population: Mean age 59 ± 10 years, 70% male, 80% alcohol-related cirrhosis, mean MELD-Na score 16.1 ± 4.2. Results published in Journal of Hepatology, demonstrating improved CLIF-C-AD and MELD scores with positive impact on healthcare costs and patient quality of life.
Current Trial: £2 million NIHR-funded randomized controlled trial across 15 NHS trusts with 200+ patients to validate clinical effectiveness and cost-effectiveness. Led by UCL Division of Medicine and managed by the Comprehensive Clinical Trials Unit at UCL.
CirrhoCare® is a digital therapeutic intended for assisted diagnosis, recommendations and therapeutic intervention for the management of new complications of decompensated cirrhosis.
CirrhoCare® will be applied for out-of-hospital specialist Hepatology follow-up and intervention of all adult cirrhosis patients, at risk of acute cirrhosis decompensation.
Its principle use is foreseen in patients being discharged from hospital following recovery from acute cirrhosis decompensation, for assisted diagnosis of new complications of cirrhosis and their early intervention.
Potentially preventable causes of cirrhosis decompensation when diagnosed, such as dehydration or hepatic encephalopathy, would be managed by a prescription digital therapeutic intervention by CirrhoCare®.
In patients who remain stable on CirrhoCare® Management follow-up for up to 6 months, a more standard medium-term outpatient clinical follow-up pathway could be resumed. For those who remain unstable or with signs of frequent new complications, CirrhoCare® PDT management would be continued beyond 6 months.
Critical safety information for CirrhoCare® users and healthcare professionals.
Caution: Avoid sending your clinician any critical or life-threatening message via CirrhoCare®.
Use the NHS 111 online service for immediate medical assistance, or dial 111 if you are unable to receive assistance online. Call 999 to request an ambulance in cases of life-threatening situations.
The CirrhoCare® patient care app is intended for patients who speak English as their first language and have access to an Android or iOS smartphone.
CirrhoCare® is intended only for patients who own a smartphone and are familiar with smartphone apps. Requires internet connection periodically (once every 4 hours) for data upload.
CirrhoCare® is not intended to be used as a stand-alone therapy. It does not represent a substitution for patient medication. Continue taking medications as directed by your healthcare provider.
Please write to help@cyberliver.com if you require any further information.
Comprehensive guidance for safely and effectively using CirrhoCare® system.
Patients using the prescription code complete a registration/sign up procedure as part of the onboarding process. Follow the step-by-step instructions provided in the CirrhoCare® app.
Healthcare Professionals need to be fully trained in the use of the software application. Please refer to the instructions of use link for detailed training materials.
Complete patient instructions for use v2.14 (detailed)
Download Detailed GuideNote: Documents are available for immediate download. For technical support, contact help@cyberliver.com
System requirements and supported devices for CirrhoCare® platform.
❌ Not supported on other mobile OS platforms
❌ Not supported on Huawei App Gallery
❌ Not supported on Windows Mobile
❌ Not supported on BlackBerry
For specific device compatibility information, please contact:
help@cyberliver.comContact our team to learn about CirrhoCare® and how it can transform cirrhosis care.